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This coordinated engagement across the pancreas, brain, gut, liver, and adipose tissue underlies the mechanistic rationale for dual GLP-1/GIP receptor agonists, and explains why they have been described as “super GLP-1RAs,” reflecting genuine potentiation of GLP-1 action by GIP receptor agonist co-activation
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It points to compounded GLP-1 medications prescribed by a licensed provider and dispensed through licensed 503A pharmacies as a cost-controlled alternative when a program denies coverage or a patient does not meet criteria
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